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A Look at the Pipeline of Next-Gen Anti-Obesity Drugs The future of obesity medicine is focused on combination therapies that target more than one hormonal pathway simultaneously

Ferroptosis in PCOS is accompanied by the dysregulation of mitochondrial dynamics, the promotion of an inflammatory response, and the intensification of oxidative stress (1416)

Sensitivity to 9-tetrahydrocannabinol is selectively enhanced in beta-arrestin2-/-mice

DiPasquale DM, Muza SR, Gunn AM, Li Z, Zhang Q, Harris NS, et al

This supports the idea of using different puncture performance tests to ensure reliable MN skin insertion where in vitro testing may primarily serve preclinical development, while ex vivo and in vivo tests are necessary to establish in vitro-in vivo correlation (IVIVC) and shall be replaced solely by the in vitro tests [27]

Identifying biomarkers specific to the senescence burden in each patient could allow for the development of tailored treatment plans that maximize efficacy and minimize side effects