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For example, exosomes from unstressed mouse NK cells can suppress the release of pro-inflammatory cytokines from stressed astrocytes in vitro , whereas direct intracranial administration of a miR-207 mimic recapitulates the overall antidepressant phenotype in depressed mice (Li D

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Looking only at cereals, although wheat germs are the richest source of spermidine among plant-based foods, wheat flour and bread contain much less amount, while in macaroni and noodles, the content is almost neglectable (see Fig

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Finally, the BBB participates in neurovascular communication, integrating neuronal, vascular and glial signals to adjust both blood flow and permeability according to brain metabolic needs [2,79,80,81]