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44 The corticotropin (ACTH) stimulation test is used to diagnose a variety of adrenopathic conditions, including endogenous or iatrogenic hyperadrenocorticism, as well as spontaneous hypoadrenocorticism.42, 45, 46 As a screening test for the diagnosis of naturally occurring hyperadrenocorticism, the ACTH response test has a diagnostic sensitivity of approximately 80% to 85% and a higher specificity than the LDDS test.45, 46 In a study by Kaplan and Peterson, only 15% of dogs with nonadrenal disease exhibited exaggerated response to ACTH stimulation

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When used in patients with type 2 diabetes, particularly those on insulin or sulfonylureas, dose adjustments of these concomitant medications may be necessary to reduce hypoglycemia risk

The total protein level of the red blood cell membrane, osmotic fragility, and red blood cell morphology were maintained

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