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To minimize TMAO production, it is vital to adhere to the divided dosing strategy, keeping single doses under 1,000 mg to ensure maximum small intestinal absorption and minimal spillover into the large intestine

[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Stanley C.A., DeLeeuw S., Coates P.M., Vianey-Liaud C., Divry P., Bonnefont J.P., Saudubray J.M., Haymond M., Trefz F.K., Breningstall G.N., et al

Prevention and optimal management of sarcopenia: a review of combined exercise and nutrition interventions to improve muscle outcomes in older people

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However, other research suggests that it has no benefit

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