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Ketone ester effects on biomarkers of brain metabolism and cognitive performance in cognitively intact adults 55 years old

Taken together, these findings strongly suggest the mechanistic link between iron accumulation and -syn aggregation in PD

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Animals were bred and maintained under standard housing conditions in the Cleveland Clinic Biological Resource Unit with ad libitum access to food (Envigo #2918) and water, 12 h light/12 h dark cycles, temperature between 20 and 23 C with 3070% relative humidity, and weaned between 3 and 4 weeks of age

Glucuronoxylomannan, a microbial compound, regulates expression of costimulatory molecules and production of cytokines in macrophages

Mouse major urinary proteins, primarily expressed in the liver, and circulating major urinary proteins regulate metabolism by suppressing hepatic gluconeogenesis and lipid metabolism (Charkoftaki et al., 2019)