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Closer examination revealed 211 DEGs when comparing the GR mutant strain to the WT strain, with 123 genes upregulated and 88 genes downregulated in the GR mutant strain (Figure 3B)

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( A and B ) mRNA expression levels of GLUT and SGLT transporter isoforms in BMDMs ( A ) and THP-1 cells ( B ) cells in unstimulated macrophages (green) and after treatment with classic M1 (purple) or alternative M2 (yellow) polarization stimuli for 24 hours

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This study follows the recommendations of the reporting of a disproportionality analysis for drug safety signal detection using individual case safety reports in pharmacovigilance (READUS-PV) 16