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55.00 - AOD-9604 - Research Peptide AOD-9604 is a modified peptide fragment of human growth hormone (HGH), studied for its potential in fat metabolism and regenerative applications

Affiliation: 1 College of Arts & Science, Case Western Reserve University, Cleveland, OH 44106, USA These authors share the first authorship

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In vitro studies showed that vitamin D (50-500 IU) significantly reduced mRNA levels of MMPs, NF-B, TNF-, and IL-6, while increasing IL-10 in IL-1 stimulated rat chondrocytes, indicating chondroprotective effects of vitamin D

10.1021/acschembio.9b00725

These data provide a proof of concept that a small molecule that binds to the lysine-binding domains of apo(a) can inhibit the formation of Lp(a) in vivo