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10.1016/j.cell.2011.02.013 Cell 41 HuS.FrankeR

Next, HLEB3 cells were pretreated with specific inhibitors, including chloroquine (autophagy), Fer-1 (ferroptosis inhibitor), Z-VAD-FMK (a cell-permeant pan caspase inhibitor of apoptosis), and Nec-1 s (necrosis inhibitor) after UVB stimulation

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Symptomatic oHCM is a genetic condition where patients have thickened heart muscles and reduced blood flow from the left side of the heart to the rest of the body causing shortness of breath, fatigue, and potentially life-threatening events

Lin et al., 2022), in this study this HUA animal model was used to observe the influence of pharmacological intervention with FA metabolism-targeting drugs on HUA-associated LVR and confirm the underlying mechanism

doi: 10.1053/gast.2002.36027 4 TrivellaJJohnBVLevyC