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To view a copy of this licence, visit About this article Cite this article Azizan, N., Al-Maleki, A.R., Rofiee, M.S

Cells, 8 (12), 1471

Melasma appears as brown or grey patches, commonly on the cheeks and forehead

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Chronically elevated cortisol: Promotes visceral fat accumulation specifically, the metabolically dangerous intra-abdominal fat Drives hepatic glucose output, raising fasting blood sugar Suppresses adiponectin, a hormone that improves insulin sensitivity Increases appetite for calorie-dense foods by elevating ghrelin relative to leptin Impairs thyroid hormone conversion from T4 to active T3 This is why metabolic syndrome so frequently co-presents with sleep disorders

Challenges in visceral leishmaniasis control and elimination in the developing countries: a review