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It is assumed that the induced cytotoxicity increases the cell layer leakage and facilitates a clearance of LDH and liver-specific ALT from the hepatic chamber towards the vascular circulation, which was validated by increased permeability from the hepatic chamber towards the vascular perfusion

Hypoxic conditions during expansion culture prime human mesenchymal stromal precursor cells for chondrogenic differentiation in three-dimensional cultures

Sugaya 1995

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This supports that stress responses related to stress granule dynamics are altered in TDP-43 K408R/K408R likely related to inefficient recovery

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