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found that alanine aminotransferase (ALT) normalization rate, HBV-DNA and HBeAg negative conversion rate and anti-HBe seroconversion rate of the treatment group was treated with baicalin and telbivudine were significantly higher than the control group were treated with only telbivudine, and that post-treatment markers of hepatic fibrosis, hyaluronic acid, laminin, and type III procollagen, in the treatment group differed significantly from those in the control group (Li et al., 2011)