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Background Almost half of adults worldwide now live with excess body fat, a figure projected to climb to 54% by 2035, and it drives type 2 diabetes, hypertension, dyslipidemia, osteoarthritis, and mood disorders

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Long-Term Outcomes Most users report lasting benefit after completing a full treatment protocol and appropriate rest period

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[539] Further, we continue to believe, as indicated in the CY 2026 OPPS/ASC proposed rule that, for those hospitals that are assessed a CMP, the reduction of the CMP we are finalizing if the hospital elects not to appeal CMS' findings, would offset some of the hospital financial burden, including legal fees and costs associated with challenging the impositionincluding requesting and defending a hearing before an Administrative Law Judge (ALJ) and any subsequent appeals

As described in the 2010 Celontin Prescribing Information (PI), this drug was approved for the treatment of absence seizures refractory to other drugs