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Description

This leads to the expression of the mutant huntingtin protein (mHTT) which provokes pathological changes in both the central nervous system (CNS) and periphery

Glaser, K

E.SouzaJ

Presentacin en lmina: prctica, moderna y fcil de usar

The endocrine actions of mitokines related to mitochondrial stress and adaptations are highlighted, specifically the broad functions of fibroblast growth factor 21 and growth differentiation factor 15, as well as their specific actions in regulating inter-tissue communication and metabolic homeostasis

Monitoring mtDNA copy number, deletion frequency, and mutation load offers a window into cellular metabolic health, with potential as biomarkers for predicting ART toxicity, assessing immune reconstitution, and stratifying risk for neurological, cardiovascular, and age-related complications