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384,385 Additionally, GWAS has identified several novel genetic loci associated with DPN, underscoring the complex genetic architecture underlying this condition

Karimi, et al

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Elevated levels of ROS and iron in haematopoietic cells lacking the H-ferritin gene lead to a reduction in T-cell populations ( Figure 2 ) (112)

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3 Breakdown of the blood-brain barrier in epilepsy In earlier studies, it has been proposed that seizures disrupt the normal barrier to transport or diffusion of certain chemicals between the blood and brain tissue