bacterial and host-derived glutathione are required to activate prfa Discovery of a utilization pathway in Francisella that shows functional divergence between environmental pathogenic species: Cell Host & Microbe Listeria monocytogenes utilizes glutathione and

Listeria monocytogenes utilizes glutathione and limited inorganic sulfur compounds as sources of essential cysteine Infection and Immunity Glutathione Provides a Source of Cysteine Essential for Intracellular Multiplication of Francisella tularensis PLOS Pathogens Frontiers Metabolic host responses to infection by intracellular bacterial pathogens Glutathione metabolism impacts fungal virulence by modulating the redox environment bioRxiv Allosteric GSH binding primes PrfA for DNA binding. (A and B) Download Scientific Diagram a) Regulation of PrfA expression and activation. The prfA transcript Download Scientific Diagram

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