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Acetyl-L-Carnitine has a much longer, established history of clinical research in the context of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

76 ZhangX.LevyD.KainzV.NosedaR.JakubowskiM.BursteinR

If you feel like your muscles are squeezed so tightly that they hurt like the cuff on a blood pressure kit this finding confirms your suspicions

Finally, we highlight major limitations in the current evidencesuch as heterogeneous dosing regimens, the scarcity of long-term clinical data, and insufficient mechanistic validation under MASLD conditionsand propose directions for future translational research

Subgroup analysis in terms of route, dose, and duration of treatment was performed to obtain more insights on the exploration of heterogeneity