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Both variants had similar kinetic parameters as the WT, indicating that though catalytically unchanged, the stability of these variants is markedly reduced, with G6PD Plymouth present in even lower amounts and ultimately leading to more severe clinical manifestations

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Ward MK, Feest TG, Ellis HA et al (1978) Osteomalacic dialysis osteodystrophy: evidence for a water-borne aetiological agent, probably aluminium