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coli strain XL1-Blue and purified by affinity chromatography using an elution buffer containing 200 mM imidazole, 300 mM NaCl and 50 mM sodium phosphate, pH 8.0 (refs 11, 12, 18, 33, 53)

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Recent research highlighted the significant role of long noncoding RNA (lncRNA) in the occurrence and progression of IBD [81, 82]

Tolerance of high-dose (3,000 mg/day) coenzyme Q10 in ALS

Increasing concentrations of desipramine at 0.1, 1 and 10 mmol/L significantly decreased pkc activity (Morishita and Watanabe, 1997)

WES WES was commercially performed (Centogene, Rostock, Germany) for five family members, including the single affected individual (proband: III-7), both parents (II-3 and II-4), and twin sisters (III-4 and III-5) using Illumina platform (Illumina, Inc., San Diego, CA, USA