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Effect of nusinersen on respiratory muscle function in different subtypes of type 1 spinal muscular atrophy

The involvement of mitochondria in Ca 2+ cycling regulation and ATP production makes these organelles crucial for synaptic function during neurodevelopment and in the adult brain

Di Zazzo, E., Galasso, G., Giovannelli, P., Di Donato, M

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The carbohydrate moieties on viral S-protein surface could facilitate viral internalization via innate immune factors, such as neuropilin (NRP)-1, C-lectin type receptors (CLR), and toll-like receptors (TLR), as well as the non-immune receptor glucose-regulated protein 78 (GRP78) for systemic spread of infection 61

Maintaining a balanced microbiome is believed to contribute to behavioral improvements and immune regulation