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Primary safety outcomes included symptomatic intracranial hemorrhage and mortality

Source-filter/subtractive models are inspired by the human vocal tract and dynamically filter a harmonically rich source signal (Flanagan, 2013), while sinusoidal/additive models generate sound as the combination of a set of time-varying sine waves (McAulay & Quatieri, 1986

The strongest association with vitamin B12 deficiency was among those younger than 30 years of age using PPIs for 2 or more years (OR, 8.12 [ 95% CI, 2.26 19.56]), decreasing with increasing age

Brain Res 503, 299303 (1989)