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Given the fact that PPI blocked autophagic flux in low pH condition, there was an interesting comparison showing that, the same amount of PPI caused more protein overload stress and UPR markers in pH 6.5 than pH 7.4, which was quantified by ER Tracker staining (Supplementary Figure S14f) and Q-PCR (Supplementary Figure S14g)

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Due to its ability to produce astaxanthin in large quantities, Haematococcus pluvialis has become an important research subject in the fields of biotechnology and nutrition [28]

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