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In the existing study, AZA treatment showed a significant depletion in the activity of hepatic GPx, SOD, and an insignificant reduction in CAT with a highly significant elevation in hepatic MDA level, which exerted severe oxidative stress induced by AZA that proved liver injury

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In the same way, dopamine-loaded albumin/PLGA polymeric nanoparticles in the 300400 nm size range were effectively targeted to brain and restored motor function in a mice model of PD [60]

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