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Understanding the principles of pharmacokinetics is important in medicine because knowing the pharmacokinetic characteristic of the drug allows prescribers to base dosing on both drug characteristics and the patient's physiological state

Technically, reconstitution with distilled water is possible, but the solution obtained in this way does not have bacteriostatic protection and must be used once or immediately frozen in aliquots

Reconstituted epitalon requires refrigeration at 2 to 8 degrees Celsius and remains stable for approximately 4 to 6 weeks

All animals were housed in an environment with a controlled temperature of 22 C 1 C, a relative humidity of 50% 1% and a light/dark cycle of 12/12 h

Human data is limited primarily to topical dermatological applications

10.1001/jama.2015.3058 83 PressR