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Cytokine-secreting herpes viral mutants effectively treat tumor in a murine metastatic colorectal liver model by oncolytic and T-cell-dependent mechanisms

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And protein kinase A phosphorylates hormone-sensitive lipase, the enzyme that physically breaks triglycerides apart into free fatty acids and glycerol

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Reference: Neelakantan H, Vance V, Wetzel MD, Wang HY, McHardy SF, Finnerty CC, Hommel JD, Watowich SJ (2018)