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Ellinghaus D, Jostins L, Spain SL, Cortes A, Bethune J et al (2016) Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

10.1039/D5PM00079C 93

Clustered Image Maps (CIM) and relevance networks were constructed to visualize the results of the analysis

ROS accumulation triggers OS, cellular damage, mitochondrial dysfunction, A deposition, Tau hyperphosphorylation, synaptic loss, and neuronal deathkey factors in AD progression (Aliev et al., 2004

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Orphanet J Rare Dis 2 , 16 (2007)