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Inflammatory bowel disease: cause and immunobiology

Kim ST, Chu Y, Misoi M, Suarez-Almazor ME, Tayar JH, Lu H, Buni M, Kramer J, Rodriguez E, Hussain Z, Neelapu SS, Wang J, Shah AY, Tannir NM, Campbell MT, Gibbons DL, Cascone T, Lu C, Blumenschein GR, Altan M, Lim B, Valero V, Loghin ME, Tu J, Westin SN, Naing A, Garcia-Manero G, Abdel-Wahab N, Tawbi HA, Hwu P, Oliva ICG, Davies MA, Patel SP, Zou J, Futreal A, Diab A, Wang L , Nurieva R

Intriguingly, immune-responsive gene 1 (IRG1) redirects citrate to itaconate, which synergizes with NO to block succinate dehydrogenase (SDH), forming the second breakpoint, which accumulates inflammatory succinate [14]

(2019, June 7)

The greatest sources of L-theanine in our diets are green, black and white teas, but because most people dont drink very large quantities of tea on a daily basis, L-theanine supplements can be beneficial

N.RamasamyA.PartsL.KnowlesD.et al (2013)