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doi: 10.1002/BIOF.5520250129 81 KruzelMLBacsiAChoudhuryBSurSBoldoghI

10.1016/j.exger.2018.07.021 203 SarnataroR.VelascoC

Some studies have incorporated a loading regimen with higher initial doses, followed by lower maintenance doses of 1-2mg per week

Simultaneously, gastrointestinal dysfunction is a common feature of PD and could lead to the impaired absorption of L-DOPA, which also causes the motor fluctuations of PD (Svensson et al., 2016)