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Anti-inflammatory effects of ribes diacanthum pall mediated via regulation of nrf2/ho-1 and nf-kb signaling pathways in lps-stimulated raw 264

Visualization of predicted binding pockets in the protein structure showing different potential ligand-binding sites: (a) primary binding pocket highlighted in red, (b) secondary surface pockets highlighted in blue, (c) ligand-interacting cavity highlighted in yellow with bound conformation, and (d) another potential internal binding pocket highlighted in yellow within the protein structure Figure 8

J Pharmacogn Phytochem 8:686693 Ross SM, McManus IC, Harrison V, Mason O (2013) Neurobehavioral problems following low-level exposure to organophosphate pesticides: a systematic and meta-analytic review

The activity of an enzyme can be influenced by the availability of cofactors, the concentration of substrates, the oxidative status, post-translational modifications or by inhibitors

The proposed purpose is to help protect glutathione during digestion and facilitate delivery across biological membranes