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Altogether, the increase in the amounts observed for acetate, glycerophosphocholine and uridine nucleotides in the presence of the TNAP inhibitor suggests reduction in lipogenesis that could reflect the reduction in the number of neurites per cell

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Consistently, independent isotopic labelling studies in human lung cancer indicated minimum glutamine utilization in vivo, with glucose and lactate being the main contributors to the TCA cycle 9,45

After 24 h a volume equivalent to OD 600 = 0.2/mL was harvested and centrifuged at 9 C

The lipid metabolisms including increased de novo lipogenesis and attenuation of lipolysis in the adipose tissue largely coordinate with glucose homeostasis response to insulin stimulation