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At the transcriptional level, GPX4 is regulated by the transcription factors such as NRF2, Sp1 and Tfap2c and mTORC, LCN2 upregulates both SLC7A11 and GPX4 to block ferroptosis (4851)

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Moreover, more than 95% of the metabolites and 87% of the lipids achieved a relative standard deviation (RSD) of less than 30% in the QC samples

doi: 10.3389/fcell.2022.826204, 69