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Mutagenesis was performed in the plasmid CD98 ( SLC3A2 ) (NM_002394) Human Tagged ORF Clone (Origene, RG216640) using the QuickChange II sytem (Qiagen), the primers used were: acctcggtgtcctgggccatggtgcctgtaac and gttacaggcaccatggcccaggacaccgaggt

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