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However, some biotransformation products have enhanced activity or toxic properties

doi: 10.1016/j.canlet.2020.12.004 67 IrvingBAWeissA

Nat Rev Gastroentero Hepat

Additionally, IL-6 and IL-23 can drive Th 17 differentiation, with IL-17 recruiting neutrophils that infiltrate thyroid tissue, causing direct damage to follicular epithelial cells (Stadhouders et al., 2018)