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Among them, liraglutide and semaglutide were reported to reduce body weight [4,5] and most recently once-weekly injection of semaglutide was approved for obesity treatment [6]

3.1.4 Redox stress-metabolic pathways regulating ferroptosis Additional regulators of ferroptosis include coenzyme Q10 (CoQ10), NADPH, selenium, p53, NRF2/NFE2L2, and vitamin E

Engel, S

Therefore, drugs that reach the trigeminal nerve will be transported directly to the brain while bypassing the BBB (Crowe et al., 2018, Drath et al., 2025)