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Causes of deficiency include low vitamin B12 intake, malabsorption, increased requirements, and unbalanced diets [3,4,6]

J Mol Med (Berl) 91:147155 Calabretta E, Carlo-Stella C (2020) The many facets of CD38 in lymphoma: from tumor-microenvironment cell interactions to acquired resistance to immunotherapy

one or more chemical entities e.g., nicotinamide riboside, nicotinamide mononucleotide a cell expressing NNMT followed by contacting said cell expressing NNMT one or more NNMT inhibitors (such as a cation of Formula I or IA, or otherwise disclosed herein)

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For example, Animal doses cannot establish human safety through simple conversion

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