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Chapter 11 - Curcumin and molecular targets in eye diseases

143,144 The mutated IDH1 and IDH2 proteins are endowed with a novel ability to catalyze the reduction of -KG to generate a rare metabolite, 2-hydroxyglutarate (2-HG), while consuming NADPH

Cell Chem Biol 24(11):1321-1335.e5 Bazhanova ED, Kozlov AA, Litovchenko AV (2021) Mechanisms of Drug Resistance in the Pathogenesis of Epilepsy: Role of Neuroinflammation

Moreover, when considering the relationship between high HDL-C levels and increased all cause and CV mortality, relevant factors to be evaluated are sex differences together with the presence of CVD and other comorbidities

(1) In addition to these, glutathione is also responsible for modulating the ability of depigmentation of cytotoxic agents that target melanocytes, thereby potentiating their effect and further aiding the process of skin lightening