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Current Neuropharmacology 2016 Sikiri et al

As mentioned, CYP2D6 is the natural body enzyme that breaks down antidepressants, opioids, and heart rhythm medications, just to name a few

Pain Can be felt in one area or many areas throughout the body Can be made worse when firm pressure is applied to soft tissues, or sometimes with gentle pressure such as a hug Fatigue Muscle weakness Sleep disturbances Mood changes (irritability, anxiety, depression) Difficulty concentrating Brain fog and Memory issues Gastrointestinal issues (constipation, diarrhea, IBS) Sensitivity to bright light, loud sounds, and smells Headaches What causes Fibromyalgia Symptoms

Some people stay at a lower step longer based on prescriber direction, so the written instructions on the label should guide the timing

Schedule Once-daily subcutaneous injection for the pre-blend

Insertional tendinopathy requires injection slightly lower, in the subcutaneous tissue just above where the tendon attaches to the calcaneus