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doi: 10.3390/ijms22126574 57 Delgado-RocheL.MestaF

Accessed 5/30/2026

Longitudinal analysis of contrast acuity in Friedreich ataxia

For all IF stainings, wells were imaged with a 20 objective except BrdU staining (imaged using a 10 objective)

51 As GSH is known to be present in CSF at very low concentrations (~0.2 mol/l in both healthy and PD subjects), 52 relative to brain tissue concentrations (~1 mmol/l), 7 LCModel-calculated Cr concentrations ( C measured ) were corrected ( C corrected ) using the following formula, which assumes negligible contribution of CSF GSH to the total GSH signal: Absolute GSH levels (IU) were calculated by multiplying GSH/Cr ratios by CSF-corrected absolute Cr concentrations (IU)