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Collection of fractions every 10-30 min for LC-MS/MS or HPLC quantification

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In addition to the vast inter-individual and inter-geographical differences in microbiome composition and function in the human population, the lack of a precise understanding of microbiome temporal dynamics and metabolite fluxes between the gastrointestinal lumen and the host systemic circulation presents a formidable challenge

Acute toxicity studies of SLNs in Wistar rats Acute oral toxicity studies were followed according to OECD 423 guidelines 28

[DOI] [PubMed] [Google Scholar] 61.Jacobi N., Seeboeck R., Hofmann E., et al