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Besides H3K9, multiple lysine and arginine residues of histones (such as H3R2, H3K4, H3K27, H3K79, H4R3, H4K20, and H2BK5) also undergo methylation/demethylation dynamics and exhibit pleiotropic roles in gene transcription (65)

10.1172/JCI34827 86

Interestingly, some kojic acid derivatives despite their depigmenting activities did not display tyrosinase inhibitory activitiy 419

An elevated hs-CRP Test result may indicate increased inflammatory cardiovascular risk, but it is nonspecific

3.2 DNA fragmentation In addition to lipid peroxidation, oxidative stress induces significant damage to sperm DNA, leading to DNA fragmentation ( Figure 2 )