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Witschi, A., Reddy, S., Stofer, B., & Lauterburg, B.H

10.1016/j.jep.2024.117836 42 HarringtonL

By attaching a larger molecule, like a polyethylene glycol (PEG) chain (a process called PEGylation), scientists can make the peptide too large to be easily filtered by the kidneys and can also sterically hinder the approach of degrading enzymes

Odoardi F, Sie C, Streyl K, Ulaganathan VK, Schlager C, Lodygin D, Heckelsmiller K, Nietfeld W, Ellwart J, Klinkert WE, et al