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Yuan L, Liu J, Ma W, Dong L, Wang W, Che R, et al

Peer review Peer review information Nature Communications thanks Rajesh Katare, Boyi Gan, Lu Cai and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

The hypoxia caused by these micro-clots could exacerbate ROS generation and oxidative stress, creating a vicious cycle that perpetuates the disease state (El Haouari, 2019