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Xia L, Tan S, Zhou Y, Lin J, Wang H, Oyang L, et al

To provide further support for the above experimental observations, the isothermal doseresponse CETSA (ITDR CETSA ) was also performed

Oxaliplatin-induced neurotoxicity: acute hyperexcitability and chronic neuropathy

Consistent with the established role of activated microglia in synaptic pruning, our data demonstrated a significant increase in SYNAPTOPHYSIN1 + puncta within microglia and their lysosomes, indicating enhanced engulfment of presynaptic terminals and suggesting that microglial activity under these conditions may contribute specifically to presynaptic terminal loss [93]

Non-adipocyte fatty acids are mediated primarily through the transmembrane protein CD36, fatty acid transport proteins (FATPs), and fatty acid-binding proteins (FABPs)

While these provide ALA rather than direct EPA and DHA, they contribute to overall anti-inflammatory status and support hormone balance