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It is believed that the redox homeostasis in the ER may result in ER-associated stress, which may trigger redox signaling mediators playing roles in ROS formation and consequently in the pathogenesis of various human disorders

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The gradient profile was as follows: 5% B from 0 to 0.5 min, 560% B from 0.5 to 11 min, 60100% B from 1111.1 min, maintained at 100% B until 12 min, then re-equilibrated at 5% B from 12.115 min

Psoriasis is a chronic autoimmune inflammatory condition that causes patches of skin to become red, inflamed, and bumpy

Some patients may benefit from cycling the treatment (e.g., 5 days on, 2 days off) or adjusting injection timing for better results