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This multifactorial assault on glutathione homeostasis creates a compelling rationale for exogenous support, particularly through delivery methods that ensure reliable tissue concentrations

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Additionally, we found that melatonin continued to have suppressive effects on ILC2 effector function even in the presence of MT1 and MT2 antagonists ( Figures 3BE )

J Immunol (Baltimore Md: 1950) (2000) 164(12):6495502

Springer International Publishing, Cham, pp 123 Parisy V, Poinssot B, Owsianowski L, Buchala A, Glazebrook J, Mauch F (2007) Identification of PAD2 as a gamma-glutamylcysteine synthetase highlights the importance of glutathione in disease resistance of Arabidopsis