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Expression Region: Gln21~Tyr72+Cys+Gly74~Lys226

In the case of PAP-cysteine, the extent of cellular impairment was comparable to that induced by PAP at similar doses

In addition, standardized evaluation procedures contribute to accurate recordkeeping and dependable data collection practices

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Int J Mass Spectrom

Methotrexate has the most powerful action against the human enzyme, whereas trimethoprim is most active against the bacterial enzyme and is likely to cause megaloblastic anemia only when used in conjunction with sulfamethoxazole in patients with preexisting folate or cobalamin deficiency