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The blood supply to the endometrium originates from the uterine arteries, which subsequently branch into the arcuate arteries, radial arteries, and spiral arterioles which are steroid hormone-responsive vessels ( Endometrial growth is also promoted by an increase in insulin-like growth factors (IGF) and epidermal growth factors (EGF), both of which are stimulated by rising estradiol levels during the proliferative phase (Logie et al., 2010)