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Research in animal models indicates that elevated NNMT expression is associated with reduced levels of the glucose transporter GLUT4

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Clinical, Cosmetic and Investigational Dermatology, 9 , 325

To assess cell death and proliferation, 7AAD or Ki-67 (BioLegend, 420404 and 652409) staining was performed respectively

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While the peptide demonstrated a favorable safety profile, its development as a prescription obesity medication was discontinued in 2007 after mixed efficacy results in larger trials