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The second mechanism includes the development of hyperplasia (an increase in the number of muscle fibers)

these include: Underlying bacterial infection or toxin-related rash (eg, staphylococcal scalded skin syndrome and toxic shock syndrome) Viral exanthems, including measles, rubella, human immunodeficiency virus (HIV), roseola due to human herpes-virus 6, Epstein-Barr virus and many others Irritant contact dermatitis Folliculitis Sweat-induced miliaria or transient acantholytic dermatosis (Grover disease) Erythema multiforme due to non-drug causes Idiopathic generalised pustular psoriasis (AGEP may mimic this) Non-drug-induced cutaneous lupus erythematosus Autoimmune blistering diseases Other causes of erythroderma (eg, eczema, psoriasis, and lymphoma)

(B and C) Duration in center (B, F (2,24) =5.349, p=0

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10.1371/journal.pone.0077060 142 XiaY.SunX.LuoY.StaryC