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We have previously discovered that combinations of BBB nutrient transporter ligands alanine and glutathione (A-GSH), increase the permeability of vesicular and polypeptide nanocarriers containing model cargo across the BBB

Since hormones and growth factors, including IGF-1, function to promote growth by inducing cell proliferation and survival, hormone antagonists are often investigated as means for treating abnormal cell growth such as carcinogenesis

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Of note, the ratio of fused/fragmented mitochondria in the high glucose condition very much resembled that of BIM-deficient cells (Fig

Standard labs call 200 pg/mL normal