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175 , S25S31 (2006)

HabibiNMousaATayCTKhomamiMBPattenRKAndraweeraPHet al

It also decreases heme synthesis by inhibiting -aminolevulinic acid (delta-ALA) synthetase, the enzyme that catalyzes the first step in the heme synthesis pathway, in which succinate and glycine are combined in the mitochondria of developing erythrocytes to form d-ALA

This reaction is also known as condensation, which usually occurs between amino acids

If necessary, plasma exchange or the double plasma molecular adsorption system combined with plasma exchange artificial liver support therapy may be considered